Figure 1.

Synthetic Array Tools (version 1.0) was used to normalize and score the silver (Ag)-resistant and -sensitive gene hits as a means of representing the growth differences in Escherichia coli K12 BW25113 in the presence of 100 μM silver nitrate (AgNO₃). Only those with a score greater or less than ±0.15, respectively, were selected for further analysis. Hits between ±0.15 were regarded as having neutral or non-specific interactions with Ag. The p-value was a two-tailed t-test and significance was determined using the Benjamini-Hochberg procedure; false discovery rate was selected to be 0.1. Each individual score represents the mean of 12 trials.