Table 1.
Characteristics of study participants
| Region | Malaria prevalencea, % | Woreda | Age in years, median (IQR) | Female sex, % (n/N) | Phenotypic G6PD deficiency, proportion deficient (n/N) | SNP frequency among G6PD normal individuals, proportion deficient (n/N) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A376G | G202A | |||||||||||
| Male | Female | Male hemizygotes | Female heterozygotes | Female homozygotes | Male hemizygotes | Female heterozygotes | Female homozygotes | |||||
| Gambela | 18.4 | Abobo | 13 (8–25) | 46.5 (92/198) | 7.5 (8/106) | 5.4 (5/92) | 0 (0/5) | 37.5 (3/8) | 0 (0/8) | 0 (0/5) | 11.1 (1/9) | 0 (0/9) |
| Lare | 14 (9–30) | 46.0 (91/198) | 1.9 (2/107) | 1.1 (1/91) | 8.3 (1/12) | 0 (0/8) | 12.5 (1/8) | 0 (/12) | 0 (0/8) | 0 (0/8) | ||
| Benishangul Gumuz | 10.4 | Meng | 11 (6–30) | 46.3 (93/201) | 1.9 (2/108) | 0 (0/93) | 18.2 (2/11) | 33.3 (2/6) | 16.7 (1/6) | 0 (0/11) | 17.7 (1/6) | 0 (0/6) |
| Mao-Komo | 16 (10–35) | 42.4 (84/198) | 0 (0/114) | 0 (0/84) | 0 (0/11) | 40.0 (4/10) | 0 (0/10) | 0 (0/11) | 0 (0/10) | 0 (0/10) | ||
| Amhara | 1.1 | Bahir Dar Zuria | 13 (12–14) | 46.9 (52/111) | 0 (0/59) | 0 (0/52) | 0 (0/8) | 11.1 (1/9) | 22.2 (2/9) | 0 (0/7) | 0 (0/9) | 0 (0/9) |
| Achefer | 13 (12–14) | 52.9 (55/104) | 0 (0/49) | 0 (0/55) | 0 (0/6) | 16.7 (2/12) | 0 (0/12) | 0 (0/6) | 0 (0/12) | 0 (0/12) | ||
| Jawi | 13 (12–14) | 50.5 (55/109) | 0 (0/54) | 0 (0/55) | 0 (0/10) | 12.5 (1/8) | 12.5 (1/8) | 0 (0/10) | 0 (0/8) | 0 (0/8) | ||
| Oromia | 0.7 | Adama | 13 (8.5–31.5) | 23.8 (20/84) | 0 (0/64) | 0 (0/20) | 17.9 (5/28) | 0 (0/9) | 11.1 (1/9) | 14.3 (4/28) | 0 (0/9) | 0 (0/9) |
| Goma | 25 (10–40) | 50.8 (203/400) | 0.5 (1/197) | 1.5 (3/203) | 5.0 (1/20) | 29.4 (5/17) | 5.9 (1/17) | 0 (0/20) | 5.9 (1/17) | 0 (0/17) | ||
| Total | 0.1 | – | 14 (10–30) | 46.3 (745/1609) | 1.5 (13/864) | 1.2 (9/745) | 8.1 (9/111) | 20.7 (18/87) | 8.1 (7/87) | 3.6 (4/111) | 3.4 (3/88) | 0 (0/88) |
SNP single nucleotide polymorphism
aData was obtained from the 2015 National Malaria Indicator Survey (MIS 2015). Results indicate RDT positivity among all age groups screened during the study period. SNP data for A376G and G202A (at the right end of the table) is given for the phenotypically normal individuals only. IQR, 25th–75th percentile