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. 2018 Aug 2;17:110. doi: 10.1186/s12933-018-0753-5

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Forest plot showing Hazard Ratio (HR) and 95% confidence interval for baseline covariates included in the Cox regression analysis for the incidence of cardiovascular events during follow-up (Model 2). Pooled data from DIABHYCAR and SURGENE cohorts. Quantitative covariates are expressed as qualitative dichotomous (below or above the median) variables except for UAC (normo-, micro- or macroalbuminuria) and copeptin (expressed as increasing sex and cohort specific tertiles, T1 to T3). MI: myocardial infarction. Estimated glomerular filtration rate (eGFR) calculated with the CKD-EPI equation. KDIGO categories (G1 to G5) defined by decreasing eGFR values (see methods). UAC: urinary albumin concentration. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001