Figure 10.
Comparative in vivo NIS imaging indicates differences between the PET tracer [18F]TFB and the SPECT tracer [123I]iodide. Tumors were grown to sizes of ~350 mm3 before being imaged by either (A) [18F]TFB-PET/CT or (B) [123I]iodide-SPECT/CT. Dynamic PET data were binned into time intervals comparable to sequential SPECT images. All images are maximum intensity projections overlaid on CT. Abbreviations are: bladder (B), heart (H), kidney (K), stomach (S), thyroid and salivary glands (Th + SG), and primary tumor (T). Representative images of cohorts of N = 3 are shown. Reproduced with permission from 61, copyright 2017 Springer Nature.