Table 1.
Radionuclides for SPECT and PET imaging of NIS.
| Radionuclides | T1/2 | Decay properties | Availability | Application |
|---|---|---|---|---|
| Technetium-99m | 6 h | γ : 98.6% (141 keV) | Reactor/Generator | SPECT |
| Iodine-123 | 13.3 h | γ : 83.3% (159 keV) | Specific cyclotron | SPECT |
| Iodine-131 | 8 d | β- : 89.9% (606 keV) γ : 81.7% (364 keV) |
Specific cyclotron | SPECT/ therapy |
| Iodine-125 | 59 d | γ : 6.5% (35 keV) | Specific cyclotron | Small animal SPECT |
| Iodine-124 | 4.2 d | β+: 23% (1543, 2146 keV), γ: 11-63% (0.6-1.7 MeV) | Specific cyclotron | PET |
| Fluorine-18 | 109.8 min | β+: 97% (634 keV) | Most medical cyclotron/accelerators | PET |