Table 3.

Main canonical pathways predicted to regulate the miRNA expression profile found at day 14 compared to day 3 after bone injury. Status of activation and p-value range for the association predicted, as calculated by Ingenuity pathway analysis, are indicated.

Pathways regulating miRNAs expressed at 3d versus NO
Causal networks	Predicted status	P-value
Ago2	Inhibited	2.83×10-30
Dicer	Inhibited	2.51×10-18
Ephrin receptor B6	Inhibited	1.32×10-17
Pathways regulating miRNAs expressed at 14d versus NO
Causal networks	Predicted status	P-value
Ago2	Not determined	4.12×10-41
Dicer	Not determined	2.81×10-22
Ephrin receptor B6	Not determined	6.58×10-19
Pathways regulating miRNAs expressed at 14d versus 3d
Causal networks	Predicted status	P-value
Ago2	Activated	3.47×10-40
Dicer	Not determined	1.06×10-21
Ephrin receptor B6	Activated	1.67×10-20