Figure 6.

FTY720 in combination with gemcitabine inhibited the epithelial mesenchymal transition in pancreatic cancer. (A) Representative Immunohistochemical images of E-Cadherin (upper panel) and Vimentin (lower panel). (B) Quantification of nuclear positive Vimentin expression in all the groups. p≤0.001.(C) Real time PCR data of the various EMT markers, E-Cadherin, Snail, Slug, Twist1 and Twist2 (Left to right). β-actin was served as housekeeping gene, Statistical significance was calculated using t-test, * p≤0.001, **p≤0.01 vs vehicle