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. 2018 Jun 27;8(8):2833–2840. doi: 10.1534/g3.118.300448

Figure 3.

Figure 3

Phenotypes identification of PAX4 KO rabbits. (A) Photographs of the WT and PAX4 KO rabbits at the age of 3 days old. (B) Body weight of the PAX4 KO and WT rabbits from newborn to 72 hr. (C) Blood glucose levels of the PAX4 KO and WT rabbits from newborn to 72 hr. P < 0.05 was considered statistically significant, *, P < 0.05, **, P < 0.01, ***, P < 0.005. (D) Survival curves of the PAX4 KO and WT rabbits. (E) H&E-staining, insulin immunohistochemistry and glucagon immunohistochemistry of the pancreas sections from the PAX4 KO and WT rabbits. WT: wild type control; PAX4+/−, heterozygous PAX4 gene knockout rabbits; PAX4−/−, homozygous PAX4 gene knockout rabbits.