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The synthesis scheme of CBB3001.
A. The structure of tranylcypromine (trans-2-phenylcycpropylamine).
B. Scheme for chemical synthesis of CBB3001: i) a) Boc2O, triethylamine, DMAP, DCM; b) Trimethylsulfoxonium iodide, NaH, DMSO. ii) a) Zn, HCl (aq), i-PrOH; b) Boc2O, TEA, dichloromethane (DCM). Compound 3 is CBB3001.
C. The structure of CBB3001.
