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. 2018 Jun 18;9(7):1206–1212. doi: 10.1039/c8md00192h

Table 3. Minimum inhibitory concentrations at 48 h for DFO, DFP and DIBI in RPMI.

Microorganism MIC
DIBI
DFP
DFO
μg mL–1 μM b μMFe c μg mL–1 μM μMFe c μg mL–1 μM μMFe c
S. aureus ATCC 43300 a 4 4.06 1.35 40 288 96 >1280 >1949 >1949
A. baumannii ATCC 19606 2 2.03 0.67 80 575 192 >1280 >1949 >1949
C. albicans ATCC SC5314 2 2.03 0.67 160 1150 383 >1280 >1949 >1949

aMethicillin-resistant Staphylococcus aureus (MRSA).

bConcentration of 5 based on 24 mol% content in DIBI.

cMIC value normalized for maximum amount of iron bound by each chelator, assuming octahedral coordination with the following (ligand : Fe) ratios: DFO (1 : 1), DFP (3 : 1), DIBI (3 : 1). The ratio for DIBI is expressed according to the tris-chelate complexes of 5.