Table 2. ITC derived thermodynamic parameters for the binding of mercaptoacetate thioesters 8 and 9 with L1 at 25 °C, pH 7.0.

Compd	K d (μM)	N (site)	ΔH (kcal mol–1)	TΔS (kcal mol–1)	ΔG (kcal mol–1)
8	5.5	0.49	–16.78	–9.60	–7.18
9	19.7	0.71	–28.24	–21.81	–6.43