Skip to main content
. 2017 Dec 6;9(3):409–436. doi: 10.1039/c7md00526a

Table 8. Cytotoxicity data of RAS complexes.

Complex graphic file with name c7md00526a-u12.jpg graphic file with name c7md00526a-u13.jpg IC50 (μM)
HCT116 SW480 AGS KATOIII
2.84 Benzene 4-OMe 288 ± 44 155 ± 4 300 ± 10 213 ± 24
2.85 Toluene — 175 ± 22 62.1 ± 17.9 117 ± 10 103 ± 21
2.86 Cymene — 25.5 ± 4.0 27.0 ± 12.0 12.4 ± 1.7 14.2 ± 2.5
2.87 Hexamethylbenzene (HMB) — 5.76 ± 1.22 34.7 ± 19.3 3.04 ± 0.91 13.7 ± 5.0
2.88 1,3,5-Triisopropylbenzene (TPB) — 1.19 ± 0.12 4.07 ± 1.35 1.01 ± 0.07 1.22 ± 0.24
2.89 1,3,5-Triisopropylbenzene (TPB) graphic file with name c7md00526a-u14.jpg 3.48 ± 0.36 5.32 ± 2.09 1.16 ± 0.28 1.86 ± 0.24
2.90 1,3,5-Triisopropylbenzene (TPB) graphic file with name c7md00526a-u15.jpg 6.87 ± 1. 11 13.9 ± 5.5 3.07 ± 0.72 3.89 ± 0.15
2.91 1,3,5-Triisopropylbenzene (TPB) graphic file with name c7md00526a-u16.jpg 5.76 ± 0.13 11.0 ± 4.7 2.76 ± 0.82 3.28 ± 1.12
2.92 Hexamethylbenzene (HMB) graphic file with name c7md00526a-u17.jpg 3.05 ± 0.26 16.0 ± 6.1 1.95 ± 0.40 2.22 ± 0.35
Oxaliplatin 1.22 ± 0.18 1.08 ± 0.36 n.d. n.d.
Cisplatin n.d. n.d. 34.7 ± 0.8 8.64 ± 0.11