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| ||||||
| Compound | n | R 1 | R 2 | % Inh (1 μM) | K d (nM) | # kinases ≥90% Inh |
| UNC5052 | 1 |
|
|
97.3 | 370 | 4 |
| UNC5135 | 1 |
|
|
99.9 | 460 | 6 |
| UNC5391 | 1 |
|
|
93.1 | 730 | 7 |
| UNC5112 | 1 |
|
|
35 | — | 0 |
| UNC5124 | 2 |
|
|
100 | — | 13 |
