Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
| ||||||||||||
| Compound | R 1 | # kinases ≥90% Inh | Nek1 | Nek2 | Nek3 | Nek4 | Nek5 | Nek6 | Nek7 | Nek9 | Nek10 | Nek11 |
| % inhibition (1 μM) | ||||||||||||
| UNC5452 |
|
18 | 99.8 | 0 | 0 | 4 | 1 | 1 | 0 | 0 | 17 | 0 |
| UNC5023 |
|
42 | 62 | 0 | 14 | 0 | 44 | 4 | 0 | 22 | 69 | 24 |
| UNC5427 |
|
20 | 15 | 0 | 4 | 16 | 2 | 0 | 10 | 14 | 71 | 17 |
| UNC5462 |
|
1 | 12 | 16 | 16 | 0 | 31 | 0 | 20 | 28 | 15 | 0 |
| UNC5337 |
|
4 | 0 | 74 | 19 | 0 | 8 | 0 | 0 | 0 | 30 | 0 |
