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. 2017 Dec 8;9(1):44–66. doi: 10.1039/c7md00510e

Table 9. BAY 61-3606 and structural analogues with reported Nek1 and Nek4 activity values.

Inline graphic
Compound BAY 61-3606 BAY derivative 1 BAY derivative 6 BAY derivative 8 BAY derivative 21 BAY derivative 28
nM % Inhibition (1 μM)
NEK1 159 8 9 9 9 11
NEK4 25 7 15 13 13 7