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. 2018 Apr 20;126(4):047009. doi: 10.1289/EHP1743

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Line graph with 95 percent prediction intervals plotting cognitive deficits (y-axis) across CPF biomarker of exposure (x-axis). — Predictions of spatial memory cognitive deficit (Morris water maze latency to platform) for the rat. Dashed lines represent 95% prediction intervals, solid circles (•) represent reported plasma chlorpyrifos (CPF) concentrations from Terry et al. (2007) for the rats dosed subcutaneously every other day at 2.5 and $18 mg / kg$ . ${BM}_{CPF}$ corresponds to peak plasma CPF biomarker of exposure used in Equation 2. Horizontal and vertical dashed lines demonstrate the threshold biomarker of exposure for a 15% cognitive deficit.