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. 2018 Apr 20;126(4):047009. doi: 10.1289/EHP1743

Figure 7.

Three line graphs each plotting oral total absorbed dose in milligrams per kilogram, inhalation total absorbed dose in milligrams per kilogram, and dermal total absorbed dose in milligrams per kilogram (y-axis) across fraction of the day exposed (x-axis).

External exposure space using the preliminary benchmark dose giving rise to a 15% cognitive deficit (BMD15) and lower limit benchmark dose giving rise to a 15% cognitive deficit (BMDL15)for humans. Boundaries for the BMD15 and BMDL15 were derived from Equation 4 when the external exposure scenario gives rise to a chlorpyrifos (CPF) brain concentration at the proposed BMD15 and BMDL15 in the human. Fraction of day exposed (FOD) represents how much of the day a human is exposed to the total applied dose (TAD). Red (square hatching), orange (no hatching), and green (diagonal hatching) shading indicate exposure scenarios that fall above the BMD15CD, between the BMD15CD and the BMDL15CD, and below the BMDL15CD, respectively.