Table 4.

The five dbGaP (Database of Genotypes and Phenotypes) categories most significantly associated with differentially methylated genes in newborn cord blood, maternal blood, and common to both, ranked by adjusted p-value (adj p-value).

dbGaP category	p-Value	Adj p-value
	Newborn cord blood
Body mass index	$8.3\times {10}^{-4}$	0.0988
Atrial fibrillation	0.0026	0.0988
Hypertension	0.0029	0.0988
Heart function testsa	0.0041	0.1094
Sleep	0.0073	0.1611
	Maternal blood
Body mass index	$9.0\times {10}^{-8}$	$2.0\times {10}^{-5}$
Blood pressure	$3.5\times {10}^{-7}$	$3.8\times {10}^{-5}$
Body weight	$1.9\times {10}^{-5}$	0.0014
Albumins	$9.2\times {10}^{-5}$	0.0051
Hematocrit	0.0006	0.0201
	Common to newborn cord blood and maternal blood
Heart failure	0.0135	0.1758
Platelet count	0.0288	0.1758
Forced expiratory volume	0.0319	0.1758
Monocyte chemoattractant protein 1	0.0329	0.1758
Respiratory function testsa	0.0382	0.1758

Note: Differentially methylated genes were analyzed using Enrichr, as described in the Methods. dbGaP, Database of Genotypes and Phenotypes.

^aThe heart function tests and respiratory functions tests categories include genes that have been associated with affecting the outcomes of measurements for normal heart and respiratory function, respectively.