Table 4. In vivo pharmacokinetic characterization of 29 in mice.

	29
	3 mg kg–1 IV a	25 mg kg–1 p.o. b
C max (μM)		2.8
AUClast (μM h)	2.3	5.1
t 1/2 (h)	5.0	1.0
Cl (mL min–1 kg–1)	45
V ss (L kg–1)	6.3
F		27%

^a5% DMAC/76% PEG400/19% water; Balb/C; male.

^b5% DMAC/9.5% EtOH/76% PEG300/9.5% TPGS; Balb/C; male.21