Skip to main content
. 2016 Nov 15;8(1):202–210. doi: 10.1039/c6md00523c

Table 2. IC50 values for the inhibition of TSPO WT and TSPO A147T over-expressing 293T cell viability.

Compound TSPO WT IC50 (μM) TSPO A147T IC50 (μM) TSPO A147T IC50/TSPO WT IC50
PK 11195 67.4 ± 10.5 69.15 ± 2.6 1.0
DPA-713 >100 >100 n/a
XBD-173 29.5 ± 3.5 26.2 ± 3.3 0.9
3b >100 >100 n/a
5a 23.7 ± 1.0 22.9 ± 1.1 1.0