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. 2016 Nov 15;8(1):202–210. doi: 10.1039/c6md00523c

Table 3. IC50 values for the inhibition of TSPO WT and TSPO A147T over-expressing 293T cell proliferation.

Compound TSPO WT IC50 (μM) TSPO A147T IC50 (μM) TSPO A147T IC50/TSPO WT IC50
PK 11195 >100 >100 n/a
DPA-713 >100 >100 n/a
XBD-173 >100 >100 n/a
3b >100 >100 n/a
5a 50.5 ± 5.0 47.1 ± 1.2 0.9