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| Enzyme experiment |
Cell experiment |
|||
| Compound | IC50 (μM) | Concentration (μM) | Survival rate (%) | Percentage of inhibition (%) |
| SYSU-00440 | 1.30 ± 0.28 | 1 | 94.72 ± 5.82 | 54.34 ± 3.17 |
| ||||
| SYSU-00464 | 4.10 ± 0.32 | 10 | 97.13 ± 4.11 | 20.97 ± 2.97 |
| ||||
| SYSU-00469 | 4.68 ± 0.08 | 1 | 93.00 ± 3.70 | 66.66 ± 1.18 |
| ||||
| NLG8189 a | 696.7 ± 1.5 | |||
aNLG8189 was used as the positive control.
