Fig 4. Differential expression of genes involved in retinoid processing and putative interactions with the PPARα/RXRα pathway and lipid signalling in male livers that are associated with parental high dietary ARA levels.

Filled shapes in the figure represent overlapping differentially expressed genes between RefSeq and Ensembl annotation. Shapes that are highlighted with glow underlie gene expression information exclusively from Ensembl annotation (S4 Table); acaca (acetyl-CoA carboxylase alpha), aclya (ATP citrate lyase a); acox1 (acyl-CoA oxidase 1, palmitoyl; alias: peroxisomal acyl-CoA oxidase 1); aldh1a2 (aldehyde dehydrogenase 1 family, member A2); bco1 (beta-carotene oxygenase 1); crabp2b (cellular retinoic acid binding protein 2, b); dagla (diacylglycerol lipase, alpha); dgkza (diacylglycerol kinase, zeta a), elovl4b (ELOVL fatty acid elongase 4b); fabp7a (fatty acid binding protein 7, brain, a); fasn (fatty acid synthase); helz2 (helicase with zinc finger 2, transcriptional coactivator); lrata (lecithin retinol acyltransferase a (phosphatidylcholine-retinol O-acyltransferase)); lratb (lecithin retinol acyltransferase b (phosphatidylcholine-retinol O-acyltransferase)); pparaa (peroxisome proliferator-activated receptor alpha a); prkcq (protein kinase C, theta); rbp2b (retinol binding protein 2b, cellular); rdh1 (retinol dehydrogenase 1); retsat (retinol saturase (all-trans-retinol 13,14-reductase)); rxraa (retinoid X receptor, alpha a); scarb1 (scavenger receptor class B, member 1); srebf1 (sterol regulatory element binding transcription factor 1); vldlr (very low density lipoprotein receptor).