Table 2. Levodopa encapsulation efficiencies (EE), percent lipid recoveries, and percent levodopa loadings of PEGylated and targeted liposome groups prepared at 40 °C.
Liposome groups | % EE | % lipid recovery | % drug loading |
(2%) PEG/LUV | 71.60 ± 0.65 | 47.77 ± 0.37 | 36.92 ± 0.33 |
(4%) PEG/LUV | 74.57 ± 1.04 | 49.05 ± 0.18 | 38.01 ± 0.63 |
(0.35%) MD-(4%) PEG/LUV | 71.38 ± 0.21 | 52.46 ± 0.19 | 33.68 ± 0.49 |
(0.7%) MD-(4%) PEG/LUV | 92.47 ± 2.70 | 52.24 ± 0.19 | 44.25 ± 0.33 |
(20 μM) GSH-(0.7%) MD-(4%) PEG/LUV | 72.88 ± 0.60 | 50.13 ± 0.17 | 36.34 ± 0.17 |
(40 μM) GSH-(0.7%) MD-(4%) PEG/LUV | 83.76 ± 2.57 | 51.16 ± 0.17 | 40.93 ± 1.39 |