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. 2018 Aug 2;13(8):e0199810. doi: 10.1371/journal.pone.0199810

Table 4. Differences at end of treatment in alpha diversity and median relative abundance of taxa between subjects who had or did not have a confirmed recurrence of C. difficile during the study.

Alpha diversity Recurrence No recurrence P-value
n 11 69
Chao Mean 280 365 <0.05
Stdev* 81.6 133
Shannon Mean 2.89 3.67 <0.05
Stdev 0.89 1.11
PD Mean 7.33 10.56 <0.01
Stdev 1.04 3.94
Median Relative Abundance Recurrence No recurrence P-value
Taxa higher in subjects without recurrence
Firmicutes 3.18E-02 1.11E-01 <0.05
o_Clostridiales 1.57E-02 8.85E-02 <0.05
    f_Lachnospiraceae <LLD 2.68E-03 <0.05
      g_Blautia <LLD 1.91E-04 <0.05
    f_Ruminococcaceae <LLD 6.70E-04 <0.05
Taxa higher in subjects with recurrence
Proteobacteria
c_Gammaproteobacteria 5.70E-01 1.60E-01 <0.05
f_Enterobacteriaceae 5.70E-01 1.05E-01 <0.05
g_Erwinia 5.74E-04 9.57E-05 <0.05
g_Klebsiella 7.57E-02 5.74E-03 <0.05
Klebsiella oxytoca 3.11E-03 9.57E-05 <0.05
g_Salmonella 5.26E-04 <LLD <0.01
Salmonella enterica   5.26E-04 <LLD <0.01

*Stdev = standard deviation.

PD = phylogenetic diversity.

c = class, o = order, f = family, g = genus, s = species.