Table 2. Baseline and evolution of the biological parameters of the 50 patients with the 3 time-point available data.

Parameters		pre-LT	D 7	D 28
Platelets (109/L)*		70.5 [51;119]	88 [54.3;122.5]	204 [136;298]
Leukocytes (109/L)		4.7 [3.5;5.9]	7.5 [5;10.5]	6.1 [4.7;7.2]
Hemoglobin (g/dL)		10.1 [8.8;12.1]	11.1 [9.8;12.5]	10.9 [9.8;11.9]
Total bilirubin (μM)*		54 [29;128]	35 [24;65]	15 [9;21]
Conjugated bilirubin (μM)*		30 [16;68]	22 [14.5;45]	16.5 [12.8;21]
Creatinine (μM)		69.5 [59.3;97.5	65 [46.8;85]	77.5 [63.5;94.5]
Alanine aminotransferase (UI/L)*		183 [41;327.8]	89 [53.5;165.8]	23.5 [14.8;34.8]
Prothrombin time*$		30 [22.8;46]	81 [71;90.8]	90 [80;96]
Factor V (%)*$		26.5 [18;37]	61.5 [50.5;90]	93 [82.5;103]
Fibrinogen (g/L)*$		1.6 [1.2;2.4]	3.4 [2.92;4.2]	4.45 [3.8;5.3]
TAT complexes (ng/mL)*$		39.79 [30.7;62]	32.22 [17.21;44.04]	28.82 [16.08;50.79]
Platelet aggregation (%)	5μM ADP*	42 [16;62.5]	49 [23;71]	65.5 [52;75.8]
	10μM ADP*	58 [32.5;71.5]	61 [45;75]	73 [62.5;78.8]
	20μM TRAP	48 [19.5;71]	50 [28;73]	61 [32.5;73]
	1.5 mM Arac acid	19 [8;58.5]	48 [17;65.3]	68 [41;75]
	1 μg/mL Collagen	39 [14;59]	31 [17.5;68.5]	59.5 [25.3;72.8]
Platelet agglutination (%)	1 mg/mL Ristocetin	63 [29.5;84.5]	74 [56;91]	78 [60.3;88]
Platelet Microvesicles annexinV positive	/μL plasma	199 [79 ;357]	185 [97 ;348]	514 [193;980.3]
	%/total platelet count	0.26 [0.11 ;0.56]	0.2 [0.12 ;0.47]	0.22 [0.1 ;0.46]
CD62P positive platelets (%)	TRAP activation	89.7 [79.3;94.7]	84.1 [76.8;89.4]	89.5 [82.9;93.2]
Platelet-Leukocyte complexes (%)		20.7 [11.9;29.3]	13.7 [7.7;21]	25.7 [14.5;35]
CD40L (ng/mL) *$		0.89 [0.48;1.39]	0.46 [0.24;0.62]	0.88 [0.5;1.27]
sCD62P (ng/mL)		2.1 [1. 6;2.9]	1.4 [1.2;2]	1.7 [1.4;2.2]
CD34+ cells (/mL)		765 [385;1255]	810 [330;1655]	1575 [987.5;2875]

Data are expressed as median values [1^st-3^rd interquartiles]

*significant linear time effect (p-value < 0.0001)

$ significant quadratic time effect (p-value < 0.0001).

TAT and CD40L were performed in a subgroup of 27 patients.