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. 2017 Jan 30;8(3):616–620. doi: 10.1039/c6md00683c

Table 2. Inhibitory potency against FAAH.

Inline graphic
Compound R Inhibition of FAAH IC50 a (μM)
17 H 0.11
26 5-F 0.13
27 5-Cl 0.41
28 5-CH3 0.70
29 5-OCH3 0.36
30 5-CN 0.97
31 4-F 0.11
32 6-F 0.046
33 7-F 0.052
34 0.41
38 0.18

aValues are the means of at least two independent determinations, errors are within ±20%.