Table 2. Baseline characteristics according to percent changes in eGFR during the (a) 2-year or (b) 3-year baseline period.
| Percent changes in eGFR (%) | ||||
|---|---|---|---|---|
| ≤ −53 | > −53, ≤ −30 | > −30, ≤ 0 | > 0 | |
| (a) 2-year baseline period (n = 1868) | ||||
| N | 70 | 137 | 1222 | 392 |
| ESRD events (n [%]) | 48 (68.6) | 32 (23.3) | 47 (3.7) | 6 (1.5) |
| Death (n [%]) | 4 (5.7) | 16 (11.7) | 75 (6.1) | 34 (8.7) |
| Age (years; mean [SD]) | 55 (12.1) | 61 (11.8) | 61 (11.0) | 60 (12.1) |
| Men (n [%]) | 42 (60.0) | 82 (59.9) | 723 (57.0) | 223 (56.9) |
| UACR (mg/g; median [IQR]) | 2377 (1230, 4019) | 236 (25, 1284) | 18 (9, 68) | 17 (8, 59) |
| eGFR (mL/min/1.73 m2; mean [SD]) | 58 (26.8) | 72 (36.2) | 80 (23.1) | 71 (22.9) |
| Systolic BP (mmHg; mean [SD]) | 140 (22.7) | 138 (21.3) | 133 (19.5) | 132 (19.0) |
| Diastolic BP (mmHg; mean [SD]) | 78 (13.4) | 78 (11.4) | 76 (28.0) | 76 (11.2) |
| History of CVD (n [%]) | 7 (10.0) | 16 (11.7) | 131 (10.3) | 35 (8.9) |
| HbA1c (%; mean [SD]) | 8.6 (2.3) | 8.4 (2.2) | 8.0 (1.7) | 7.8 (1.8) |
| Follow-up (years; mean [SD]) | 5.1 (2.4) | 5.2 (2.0) | 6.6 (3.3) | 6.8 (3.6) |
| (b) 3-year baseline period (n = 2001) | ||||
| N | 79 | 202 | 1385 | 335 |
| ESRD events (n [%]) | 46 (58.2) | 29 (14.4) | 33 (2.4) | 2 (0.6) |
| Death (n [%]) | 10 (12.7) | 22 (10.9) | 69 (5.0) | 27 (8.1) |
| Age (years; mean [SD]) | 57 (12.0) | 61 (12.1) | 61 (10.8) | 59 (11.9) |
| Men (n [%]) | 52 (65.8) | 109 (54.0) | 797 (57.6) | 201 (60.0) |
| UACR (mg/g; median [IQR]) | 1925 (478, 3329) | 98 (18, 690) | 17 (9, 56) | 15.3 (8, 44) |
| eGFR (mL/min/1.73 m2; mean [SD]) | 58 (26.2) | 79 (31.4) | 80 (22.8) | 72 (22.1) |
| Systolic BP (mmHg; mean [SD]) | 139 (21.6) | 137 (20.5) | 132 (19.1) | 131 (17.8) |
| Diastolic BP (mmHg; mean [SD]) | 80 (11.3) | 75 (11.0) | 76 (27.0) | 75 (11.4) |
| History of CVD (n [%]) | 9 (11.4) | 24 (11.9) | 124 (9.0) | 27 (8.1) |
| HbA1c (%; mean [SD]) | 8.4 (2.1) | 8.3 (2.0) | 7.9 (1.7) | 7.5 (1.7) |
| Follow-up (years; mean [SD]) | 4.2 (1.8) | 4.5 (2.2) | 5.7 (3.1) | 5.7 (3.4) |
ESRD, end-stage renal disease; UACR, urine albumin-to-creatinine ratio; eGFR, estimated glomerular filtration rate; BP, blood pressure; CVD, cardiovascular disease; SD, standard deviation; IQR, interquartile range.