Table 2. The VEGFR-2 inhibitory activity of the target compounds.
Entry | VEGFR-2 IC50 a (μM) |
8a | 0.87 ± 0.06 |
8j | 0.53 ± 0.09 |
8l | 0.29 ± 0.02 |
8u | 1.22 ± 0.12 |
Sorafenib | 0.95 ± 0.09 |
aIC50 values are the mean ± S.D. of three separate experiments.