Table 3. The docking results of the target compounds.

Entry	ΔG a	K i b	Entry	ΔG a	K i b
8a	–9.53	0.104	8l	–10.52	0.019
8b	–8.53	0.561	8m	–9.65	0.084
8c	–9.00	0.253	8n	–9.20	0.179
8d	–8.95	0.274	8o	–9.56	0.098
8e	–9.66	0.082	8p	–9.10	0.214
8f	–9.14	0.198	8q	–8.59	0.503
8g	–9.32	0.147	8r	–9.76	0.069
8h	–9.37	0.135	8s	–8.59	0.505
8i	–9.61	0.090	8t	–8.31	0.815
8j	–10.28	0.029	8u	–10.27	0.030
8k	–9.42	0.125	8v	–9.45	0.119
Sorafenib	–11.03	0.008
Axitinib	–9.15	0.195

^aBinding free energy (kcal mol^–1).

^bInhibition constant (μM).