Table 2. Inhibition of recombinant PKCζ, PKCι and iNOS induction in RAW 264.7 macrophage cells.

Cpd #	Cell-free assay		Inhibition of iNOS induction in RAW 264.7 macrophage cells		MTT assay using RAW 264.7
	IC50vs. PKCζa (μM)	% inhibition of PKCι at 20 a μM	% inhibition at 7.5 a μM	IC50 a μM	% living cells at 7.5 μM of the test compound a
2a	6.5	9.3	45	ND	91
2b	6.2	24.94	62.4	ND	99
2c	<0.1	18.6	34	ND	96
2d	<0.1	22.8	42.8	ND	91
2e	0.4	29	31.5	ND	86
2f	21.3	30.5	34	ND	92
2g	4.3	14.85	31.4	ND	88
2h	<0.1	27.6	100	0.3	94
A (4h in ref. 18)	2.9	—	86	2.9	—
B (4k in ref. 18)	<0.1	—	87	3.1	—
Curcumin	—	—	97	0.8	—

^aValues are mean values of at least two experiments; standard deviation <15%; ND: not determined.