Fig. 2. Protein regions which contribute to affinity and selectivity for protease ligands, mapped on bound ZK-807834. (a) Regions relevant for affinity: polar protein field (cyan), lipophilic protein field (orange). (b) Regions relevant for selectivity: polar field points (blue), lipophilic protein field (yellow), unstable water sites (red). Gene names of the proteases, in which these field points are present, are marked with the respective colors, as that of the fields.
