Table IV.

Histone acetylation markers in monocytes and macrophages in atherosclerosis.

Enzyme	Expression in atherosclerosis	Target genes
HDAC7	Increased	IL-6, MCP-1
P300	Decreased	Transcription regulation
HDAC9	Increased	MMP12; ABCA1, ABCG1, PPAR-γ

HDAC, histone deacetylase; IL, interleukin; MCP-1, monocyte chemoattractant protein 1; ABCA1, adenosine triphosphate-binding cassette subfamily A member 1; adenosine triphosphate-binding cassette subfamily G member 1; PPAR-γ, peroxisome proliferator-activated receptor-γ.