Figure 1.

CXCL9 gene overexpression promotes the pathological process of prostate cancer in mice. (A) Hematoxylin eosin staining was used to detect histological alterations in two models of chemically induced mice at different time points (0, 16, 20 and 24 weeks; magnification, ×400). (B) Immunohistochemical staining of PCNA was used to detect cell proliferation in the two models (magnification, ×400). CXCL9, CXC motif chemokine ligand 9; DMAB, 3,2′-dimethyl 4-aminobiphenyl; PCNA, proliferating cell nuclear antigen.