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. 2018 Jun 26;18(2):2061–2067. doi: 10.3892/mmr.2018.9224

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Copyright: © Zhai et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Effects of TIMP-3 on the activity of MMP-2 and MMP-9. (A) Activity of MMP-2 and MMP-9 was detected by gelatin zymography. (B) Activity of MMP-2 was reduced following treatment with 10, 30 and 100 ng/ml TIMP-3. (C) Activity of MMP-9 was reduced following treatment with 30 and 100 ng/ml TIMP-3. *P<0.05, **P<0.01 and ***P<0.001, vs. untreated control. MMP, matrix metalloproteinase; TIMP-3, tissue inhibitor of MMP-3.