Table I.
Factor | n | Claudin-2 (high) | Claudin-2 (low) | P-value | n | Claudin-5 (high) | Claudin-5 (low) | P-value |
---|---|---|---|---|---|---|---|---|
Gastric carcinoma tissue | 100 | 37 | 63 | 0.374 | 100 | 47 | 53 | <0.01 |
Non-neoplastic tissue | 100 | 41 | 59 | 100 | 19 | 81 | ||
Age, years | ||||||||
≤60 | 29 | 10 | 19 | 1.000a | 27 | 15 | 12 | 0.261a |
>60 | 71 | 27 | 44 | 73 | 32 | 41 | ||
Histological grade | ||||||||
Well-differentiated | 35 | 12 | 23 | 1.000a | 32 | 16 | 16 | 0.614a |
Moderately and poorly-differentiated | 65 | 25 | 40 | 68 | 31 | 37 | ||
Lymph node metastasis | ||||||||
+ | 46 | 16 | 30 | 0.368 | 39 | 15 | 24 | <0.01 |
− | 64 | 21 | 43 | 61 | 32 | 29 | ||
Ki67 | ||||||||
+ | 29 | 11 | 18 | 0.232a | 27 | 12 | 15 | 0.443a |
− | 71 | 26 | 45 | 73 | 35 | 38 | ||
Clinical stage | ||||||||
I–II | 27 | 11 | 16 | 1.000a | 27 | 15 | 12 | 0.863a |
III–IV | 73 | 26 | 57 | 73 | 32 | 41 |
No statistical significance was observed with the χ2 test/χ2 goodness-of-fit test.