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(A) Effect of RPM on the cell proliferation of HUVECs at different concentrations for 48 h. **P<0.01 vs. 0 nM RPM, ***P<0.001 vs. 0 nM RPM. (B) Proliferation of HUVECs after 100 nM RPM treatment at different time points. *P<0.05, **P<0.01, ***P<0.001. RPM, rapamycin; HUVEC, human umbilical vein endothelial cell; OD, optical density.
