Table II.
A, Downregulated DEGs | ||
---|---|---|
Gene symbol | Log fold-change | Adjusted P-value |
TGFBR2 | −1.19 | 3.30×10−4 |
CFTR | −1.16 | 1.03×10−3 |
CXCL1 | −1.14 | 5.16×10−4 |
TGM2 | −1.11 | 4.73×10−5 |
THBD | −1.11 | 4.73×10−5 |
EPAS1 | −1.10 | 4.13×10−4 |
AQP3 | −1.10 | 1.00×10−5 |
CD9 | −1.07 | 3.03×10−3 |
ALDH1A1 | −1.03 | 4.22×10−3 |
RRAD | −1.01 | 1.52×10−4 |
NEDD9 | −0.99 | 3.32×10−4 |
CX3CL1 | −0.98 | 6.32×10−5 |
ANXA1 | −0.97 | 4.15×10−4 |
CNN2 | −0.95 | 3.65×10−4 |
SLC16A5 | −0.95 | 1.53×10−4 |
LAMB3 | −0.94 | 2.82×10−4 |
PROS1 | −0.93 | 1.49×10−3 |
FBLN1 | −0.92 | 8.81×10−4 |
SP110 | −0.89 | 1.36×10−2 |
TGFBR3 | −0.88 | 7.00×10−5 |
RNASE4 | −0.87 | 1.76×10−4 |
DMBT1 | −0.86 | 6.02×10−3 |
CSTA | −0.85 | 5.07×10−3 |
GPX3 | −0.85 | 1.10×10−3 |
CTSH | −0.85 | 3.15×10−3 |
PTGER4 | −0.85 | 3.15×10−3 |
VAV1 | −0.84 | 8.80×10−3 |
TCF21 | −0.83 | 4.99×10−4 |
F13A1 | −0.83 | 1.22×10−3 |
TACSTD2 | −0.83 | 5.82×10−4 |
CST3 | −0.83 | 2.69×10−2 |
STAT6 | −0.83 | 1.02×10−2 |
ADH1B | −0.81 | 3.64×10−3 |
ZFP36L2 | −0.81 | 6.86×10−4 |
PZP | −0.81 | 5.75×10−3 |
C3 | −0.80 | 2.70×10−2 |
CLU | −0.76 | 4.60×10−2 |
CYP4B1 | −0.75 | 3.74×10−3 |
SCGB1A1 | −0.75 | 5.88×10−3 |
FLRT3 | −0.74 | 3.15×10−2 |
PCSK5 | −0.74 | 2.91×10−3 |
CFH | −0.72 | 2.45×10−2 |
LYN | −0.72 | 1.19×10−2 |
ADRB2 | −0.71 | 6.46×10−5 |
HLA-E | −0.71 | 9.33×10−3 |
CAPN2 | −0.70 | 8.30×10−3 |
BAG3 | −0.69 | 1.44×10−3 |
TLR2 | −0.69 | 1.15×10−3 |
FBLN5 | −0.69 | 3.74×10−4 |
A2M | −0.66 | 2.23×10−2 |
C6 | −0.66 | 1.32×10−4 |
FOLR1 | −0.65 | 9.53×10−4 |
PLK2 | −0.65 | 1.92×10−4 |
HNMT | −0.63 | 1.23×10−2 |
MYO5C | −0.61 | 1.28×10−2 |
CAST | −0.61 | 1.05×10−2 |
PTGDS | −0.61 | 4.53×10−3 |
ANXA11 | −0.59 | 2.59×10−2 |
CCND1 | −0.58 | 3.88×10−5 |
EPHA2 | −0.58 | 3.88×10−5 |
SERPINA1 | −0.58 | 5.84×10−4 |
PRNP | −0.57 | 4.65×10−2 |
VAMP8 | −0.56 | 5.03×10−3 |
ADH1C | −0.54 | 1.74×10−3 |
CD81 | −0.52 | 3.13×10−3 |
IL4R | −0.51 | 3.98×10−4 |
B, Upregulated DEGs | ||
Gene symbol | Log fold-change | Adjusted P-value |
CCNB2 | 0.50 | 1.59×10−4 |
DDC | 0.50 | 1.59×10−4 |
HPRT1 | 0.50 | 1.59×10−4 |
CDC20 | 0.50 | 3.39×10−4 |
PARP1 | 0.51 | 3.92×10−3 |
FANCG | 0.51 | 3.74×10−4 |
PSIP1 | 0.51 | 3.74×10−4 |
ENC1 | 0.51 | 4.43×10−2 |
DEK | 0.52 | 2.91×10−3 |
FZD3 | 0.52 | 6.44×10−3 |
ZWINT | 0.52 | 2.34×10−4 |
UNG | 0.52 | 3.02×10−4 |
CDC7 | 0.53 | 3.98×10−5 |
MCM3 | 0.53 | 8.82×10−3 |
CHEK1 | 0.53 | 5.88×10−3 |
NRTN | 0.53 | 1.43×10−3 |
RBP1 | 0.53 | 5.99×10−4 |
MSH6 | 0.53 | 2.16×10−4 |
DTYMK | 0.54 | 6.60×10−5 |
MCM2 | 0.55 | 4.74×10−4 |
CHGB | 0.56 | 3.30×10−4 |
EXO1 | 0.56 | 3.30×10−4 |
CELSR3 | 0.56 | 8.00×10−4 |
CDKN3 | 0.56 | 7.01×10−3 |
SHMT2 | 0.56 | 1.85×10−4 |
TRIM36 | 0.56 | 1.58×10−3 |
BUB1 | 0.56 | 1.23×10−3 |
CDC6 | 0.56 | 4.94×10−5 |
USP1 | 0.57 | 5.25×10−4 |
PXMP2 | 0.57 | 3.87×10−5 |
RACGAP1 | 0.57 | 3.87×10−5 |
FKBP3 | 0.57 | 1.01×10−3 |
MAD2L1 | 0.57 | 1.01×10−3 |
DLK1 | 0.58 | 1.17×10−2 |
HDAC2 | 0.58 | 9.39×10−5 |
ASCL1 | 0.60 | 3.29×10−3 |
SOX4 | 0.60 | 1.89×10−2 |
COCH | 0.60 | 4.20×10−4 |
PRDX2 | 0.61 | 7.76×10−5 |
FANCA | 0.62 | 4.21×10−4 |
RFC5 | 0.62 | 1.00×10−5 |
ITGB3BP | 0.63 | 1.14×10−3 |
LHX2 | 0.64 | 8.68×10−4 |
MCM6 | 0.64 | 5.32×10−5 |
CKS2 | 0.65 | 1.92×10−3 |
CCNE2 | 0.66 | 2.14×10−4 |
ASNS | 0.68 | 5.25×10−5 |
CKS1B | 0.69 | 1.55×10−3 |
FBXO5 | 0.69 | 9.25×10−5 |
KCNH2 | 0.71 | 2.95×10−3 |
TPD52 | 0.75 | 1.99×10−4 |
STMN1 | 0.75 | 2.13×10−5 |
TYMS | 0.75 | 2.13×10−5 |
RRM2 | 0.76 | 6.99×10−5 |
CBX5 | 0.76 | 2.44×10−3 |
KIF11 | 0.76 | 1.09×10−3 |
SOX11 | 0.77 | 1.42×10−2 |
RECQL4 | 0.79 | 3.77×10−4 |
PCNA | 0.79 | 4.39×10−4 |
GMNN | 0.80 | 1.27×10−5 |
MYBL2 | 0.81 | 7.84×10−4 |
TTK | 0.83 | 5.23×10−5 |
TOP2A | 0.84 | 1.95×10−4 |
EZH2 | 0.85 | 7.70×10−6 |
PAFAH1B3 | 0.85 | 7.70×10−6 |
RAD54L | 0.85 | 7.70×10−6 |
TIMELESS | 0.85 | 2.82×10−5 |
GNG4 | 0.87 | 1.04×10−5 |
SPAG5 | 0.87 | 1.04×10−5 |
PTTG1 | 0.88 | 3.01×10−5 |
NELL1 | 0.92 | 3.40×10−3 |
MEST | 0.93 | 1.25×10−3 |
NOL4 | 0.93 | 2.14×10−3 |
UCHL1 | 0.94 | 3.18×10−3 |
INSM1 | 0.97 | 2.25×10−4 |
MKI67 | 0.98 | 1.13×10−3 |
PCSK1 | 0.98 | 1.20×10−2 |
BIRC5 | 1.00 | 3.28×10−5 |
RFC4 | 1.01 | 9.53×10−6 |
NEK2 | 1.01 | 9.94×10−4 |
CENPF | 1.08 | 1.84×10−4 |
CAMK2B | 1.10 | 1.89×10−4 |
ISL1 | 1.30 | 7.31×10−3 |
GRP | 1.32 | 1.16×10−2 |
DEG, differentially expressed genes.