Table II.
The median, upper and lower quartiles of plasma concentrations of ORM2, S100A9, IL-36α and SOD1in the STB, MTB and NC groups.
| Characteristic | STB | MTB | NC | P-value (STB vs. MTB) | P-value (STB vs. NC) |
|---|---|---|---|---|---|
| ORM2 (mg/ml) | 614.49 | 514.57 | 386.75 | <0.001 | <0.001 |
| Lower quartile (mg/ml) | 481.23 | 335.96 | 268.39 | ||
| Upper quartile (mg/ml) | 805.93 | 639.64 | 488.43 | ||
| S100A9 (mg/ml) | 14.90 | 5.07 | 2.55 | 0.03 | 0.001 |
| Lower quartile (mg/ml) | 11.37 | 2.70 | 1.69 | ||
| Upper quartile (mg/ml) | 19.34 | 6.95 | 3.25 | ||
| IL-36α (ng/ml) | 92.15 | 59.55 | 21.90 | 0.02 | <0.001 |
| Lower quartile (mg/ml) | 48.42 | 40.63 | 11.54 | ||
| Upper quartile (mg/ml) | 203.25 | 105.38 | 51.03 | ||
| SOD1 (mg/ml) | 771.70 | 985.75 | 1,021.03 | <0.001 | <0.001 |
| Lower quartile (mg/ml) | 648.26 | 652.7 | 638.53 | ||
| Upper quartile (mg/ml) | 913.40 | 1,257.81 | 1,290.86 |
ORM2, S100A9, S100 calcium binding protein A9; IL-36α, interleukin-36α; SOD1, superoxide dismutase 1; STB, severe tuberculosis; MTB, mild tuberculosis; NC, healthy control samples.