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Apigenin affects the PI3K/Akt pathway. H9C2 cells were treated with MI/R, and 1, 6 and 25 µM apigenin + MI/R. Western blot analysis was conducted to measure the expression levels of (A) p-PI3K and PI3K and (B) p-Akt and Akt in H9C2 cells. *P<0.05 and ***P<0.001 vs. control; ##P<0.01 and ###P<0.001 vs. MI/R. PI3K, phosphatidylinositol 3′-kinase; Akt, RAC-α serine/threonine-protein kinase; MI/R, myocardial ischemia-reperfusion; p-, phospho-.
