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LY294002 reverses the effect of apigenin (6 µM). Effect of LY294002 on (A) apoptosis and (B) expression of Bcl-2, p-mTOR, and mTOR. *P<0.05 and ***P<0.001 vs. control; ##P<0.01 and ###P<0.001 vs. MI/R, ^^P<0.01 and ^P<0.05 vs. MI/R + apigenin. MI/R, myocardial ischemia reperfusion; Bcl-2, apoptosis regulator Bcl-2; mTOR, serine/threonine-protein kinase mTOR; PI, propidium iodide; FITC, fluorescein isothiocyanate.
