Table 1. Antiviral activity of camphor-based compounds against the influenza virus A/Puerto Rico/8/34 (H1N1) in MDCK cells.
| Compound | CC50, μM | IC50, μM | SI | log P a |
| 1 | >2142.9 | 155.8 ± 18.3 | >14 | 2.71 |
| 4 | 301.9 ± 21.4 | 34.0 ± 4.2 | 9 | 4.29 |
| 5 | 137.6 ± 9.9 | 15.1 ± 1.0 | 9 | 4.85 |
| 6 | 93.9 ± 7.3 | 10.2 ± 1.4 | 9 | 5.34 |
| 7 | 580.1 ± 41.1 | 7.1 ± 0.8 | 82 | 3.53 |
| 8 | 102.9 ± 8.2 | 7.1 ± 0.5 | 14 | 3.68 |
| 9 | 100.0 ± 7.3 | 4.4 ± 0.5 | 23 | 3.26 |
| 10 | 51.6 ± 4.1 | 3.2 ± 0.4 | 16 | 3.79 |
| 11 | >852.0 | 683.1 ± 62.8 | 1 | 4.11 |
| 12 | 69.3 ± 4.9 | >34.1 | >2 | 6.78 |
| 13 | 124.7 ± 10.1 | 14.3 ± 1.6 | 9 | 4.45 |
| 14 | 69.6 ± 5.2 | 7.8 ± 0.8 | 9 | 5.02 |
| 15 | 56.4 ± 3.8 | 15.3 ± 2.0 | 4 | 5.51 |
| 16 | 552.5 ± 31.1 | 12.2 ± 1.6 | 45 | 3.36 |
| 17 | 12.6 ± 1.0 | 6.8 ± 0.9 | 2 | 3.51 |
| 18 | 48.1 ± 3.3 | 1.9 ± 0.4 | 25 | 3.09 |
| 19 | 104.7 ± 8.7 | 8.4 ± 0.9 | 12 | 3.62 |
| 20 | 149.5 ± 11.7 | >98.4 | 2 | 3.94 |
| 21 | 41.8 ± 2.2 | 7.1 ± 0.9 | 6 | 6.94 |
| 22 | >974 | >974 | 1 | 2.71 |
| 25 | >533.8 | 73.7 ± 8.5 | 7 | 3.53 |
| 26 | 508.5 ± 36.1 | 7.8 ± 1.1 | 65 | 3.36 |
| 27 | >1886.8 | >1886.8 | 1 | 0.11 |
| 28 | >1734.1 | 982.7 ± 75.3 | >2 | 0.64 |
| Rimantadine | 335.2 ± 26.8 | 67.0 ± 4.9 | 5 | |
| Amantadine | 284.1 ± 21.4 | 64.2 ± 4.7 | 4 | |
| Deitiforine | 1266.2 ± 81.5 | 208.6 ± 15.4 | 6 | |
| Ribavirin | >2000.0 | 24.6 ± 3.1 | >81.0 | |
| Oseltamivir | 160.3 ± 11.4 | 0.2 ± 0.03 | 781 |
alog P, the octanol–water partitioning coefficient, was calculated using ACDLabs/ChemSketch 12.01 (www.acdlabs.com).