Table 4. Inhibition of tubulin polymerization (IC50) by compounds 8m and 8q.
| Compound | IC50 a ± SD (in μM) |
| 8m | 1.82 ± 0.06 |
| 8q | 1.93 ± 0.03 |
| Nocodazole | 1.98 ± 0.04 |
aConcentration of drug to inhibit 50% of tubulin assembly.
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