Table 1. Core Modifications on 4-F-Phenyl-Substituted Derivativesa.

Data of standard inhibitors SB203580 (p38α MAPK) and SP600125 (JNK3) in our in-house activity assay are included.
IC50 values are the mean of three experiments.
n = 16.
n = 20.

Data of standard inhibitors SB203580 (p38α MAPK) and SP600125 (JNK3) in our in-house activity assay are included.
IC50 values are the mean of three experiments.
n = 16.
n = 20.