Table 5. Determined Melting Temperatures (Tm) for JNK3 Alone and in Complex with Inhibitors 38 and 44.
| sample | Tm (°C)a |
|---|---|
| JNK3 | 46.28 ± 0.58 |
| JNK3-38 | 53.87 ± 0.04 |
| JNK3-44 | 54.83 ± 0.04 |
Data represent mean value ± SD of a single experiment performed in triplicate. nanoDSF measurements (Figure S2, Supporting Information) were conducted using Prometheus NT.48 (NanoTemper Technologies, Munich).