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. 2018 Jul 12;3(7):7809–7831. doi: 10.1021/acsomega.8b00668

Table 5. Determined Melting Temperatures (Tm) for JNK3 Alone and in Complex with Inhibitors 38 and 44.

sample Tm (°C)a
JNK3 46.28 ± 0.58
JNK3-38 53.87 ± 0.04
JNK3-44 54.83 ± 0.04
a

Data represent mean value ± SD of a single experiment performed in triplicate. nanoDSF measurements (Figure S2, Supporting Information) were conducted using Prometheus NT.48 (NanoTemper Technologies, Munich).