Table 1.
Radiation Treatment Intent | N (%) |
---|---|
Local control in patients with residual nodal disease after definitive surgical resection | 13 (50%) |
Local control in patients with unresectable chest wall or nodal recurrence after prior mastectomy | 4 (15%) |
Pre-operative | 4 (15%) |
Palliation | 5 (19%) |
Radiation Regimen | |
Maximum dose | |
50 Gy | 5 |
60 Gy | 2 |
≥66 Gy | 19 |
Fractionation | |
Daily | 25 |
Twice daily (BID) | 1 |
TNBC | |
Yes | 10 (38%) |
No | 16 (61%) |
Response | |
PR/CR | 19 (73%) |
SD/PD | 7 (27%) |
CTO | |
n = 4 | 3 (75%) |
Toxicity | |
G3 Toxicity - overall | 14 (54%) |
G3 toxicity - daily capecitabine (n=9) | 7 (78%) |
G3 toxicity - weekday only capecitabine (n=17) | 7 (41%) |
Grade IV/V toxicity | 0 (0%) |
> one grade three non-dermatitis toxicity, Gy, Gray; TNBC, triple negative breast cancer; PR/CR partial or complete response; SD/PD Stable or progressive disease; CTO convert to operable