Table 2. Scope of the Cu(ii)/Fe3O4@APTMS-DFX promoted tetrazole synthesis of various substrates.
| ||||
| Entry | Substrate | Product | Time (h) | Isolated yield (%) |
| 1 |
|
|
1 | 98 |
| 2 |
|
|
1.5 | 95 |
| 3 |
|
|
1.5 | 93 |
| 4 |
|
|
2.5 | 92 |
| 5 |
|
|
1 | 98 |
| 6 |
|
|
2.5 | 90 |
| 7 |
|
|
4 | 85 |
| 8 |
|
|
3.5 | 83 |
| 9 |
|
|
4 | 80 |
| 10 |
|
|
5 | 80 |
| 11 |
|
|
2 | 80 |
| 12 |
|
|
1 | 95 |
| 13 |
|
|
1.5 | 93 |
| 14 |
|
|
4 | 88 |
| 15 |
|
|
5 | 75 |
| 16 |
|
|
6 | 74 |
| 17 |
|
|
5 | 77 |