Table I.

Relationship between the clinicopathological parameters and miR-1 expression in primary CRC cases (N=111).

		Expression of miR-1a
Characteristics	No. of cases	Mean	95% CI	P-value
Age (years)
<60	48	−2.441	−3.42–1.65	0.076
≥60	63	−0.903
Sex
Male	45	−1.303	−1.09–2.39	0.458
Female	66	−1.956
Tumor size (cm)
<5	78	−2.594	−5.21–1.70	0.001
≥5	33	0.858
Differentiation
Well + moderate	33	0.094	0.55–4.18	0.011
Poor	78	−2.271
Lymph node status
Negative	63	−3.082	−5.01–1.91	0.001
Positive	48	0.419
Metastasis
Negative	95	−1.543	−2.26–2.61	0.888
Positive	16	−1.717
TNM stage
I + II	55	−3.122	−4.69–1.47	0.001
III + IV	56	−0.042

^aMean of the relative expression of miR-1 is expressed as log₂ (fold change) value and 95% confidence interval (CI). CRC, colorectal cancer; microRNA-1, miR-1.