Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 May 24;40(2):693–703. doi: 10.3892/or.2018.6464

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Tamura et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Figure 1. — Tumorigenic potential of EpCAM^high/CD44⁺ colorectal cancer cells in vivo. (A) Flow cytometric analysis of a human colorectal cancer. A small EpCAM^high/CD44⁺ population was detected in the human colorectal cancer. (B) Only EpCAM^high/CD44⁺ cells had tumorigenic potential in NOD/SCID mice. (C) Flow cytometric analysis of a xenograft tumor. EpCAM^high/CD44⁺ cells gave rise to EpCAM^positive/CD44⁻ cells and reconstituted the expression profiles of the primary sample. (D) H&E staining of a primary and a xenograft tumor. The histology of the xenograft tumor was the same as that of the primary tumor. (E) Serial transplantation recapitulated the histology of the primary tumors.