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. 2018 May 24;40(2):693–703. doi: 10.3892/or.2018.6464

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Copyright: © Tamura et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Higher tumorigenic potential of E-cadherin⁺ colorectal CSCs. (A) Image of a mouse bearing a xenograft tumor from EC⁺ and EC⁻ colorectal CSCs and flow cytometric analyses of their phenotype. (B) Tumor weight of xenograft tumors. Error bars represent the 95% confidence interval. EC⁺ colorectal CSCs produced significantly larger tumors compared to EC⁻ colorectal CSCs. *P<0.01 (C) Histopathological analysis of xenograft tumors from EC⁺ CSCs and EC⁻ CSCs.